5-Methylcytidine
5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC50 against HSV-1 is 0.06 μM[1][2].
Product Specifications
CAS Number
[2140-61-6]
Product Name Alternative
Heat Shock Protein Inhibitor I
UNSPSC
12352005
Target
Endogenous Metabolite; HSV; Nucleoside Antimetabolite/Analog
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/5-Methylcytidine.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)C(C)=C2)=O)O[C@@H]1CO
Molecular Formula
C10H15N3O5
Molecular Weight
257.24
References & Citations
[1]de Julián-Ortiz JV, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42 (17) :3308-14.|[2]Suspène R, et al. Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase. PLoS One. 2013 Jun 20;8 (6) :e63461.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HSV-1; Human Endogenous Metabolite
Available Sizes
Curated Selection
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