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5-Methylcytidine

5-Methylcytidine is a nucleoside compound. 5-Methylcytidine has antiviral activity, and its IC50 against HSV-1 is 0.06 μM[1][2].

Product Specifications

CAS Number

2140-61-6

Product Name Alternative

Heat Shock Protein Inhibitor I

UNSPSC

12352005

Target

Endogenous Metabolite; HSV; Nucleoside Antimetabolite/Analog

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/5-Methylcytidine.html

Concentration

10mM

Purity

99.89

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)C(C)=C2)=O)O[C@@H]1CO

Molecular Formula

C10H15N3O5

Molecular Weight

257.24

References & Citations

[1]de Julián-Ortiz JV, et al. Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. J Med Chem. 1999 Aug 26;42 (17) :3308-14.|[2]Suspène R, et al. Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase. PLoS One. 2013 Jun 20;8 (6) :e63461.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

HSV-1; Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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