VU0080241
Product Specifications
UNSPSC Description
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0080241.html
Purity
99.69
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1CN(CCC1)C2=C3C(N(N=C3)C4=CC=C(C=C4C)C)=NC=N2
Molecular Weight
321.42
References & Citations
[1]Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119078/VU0080241-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119078/VU0080241-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
393845-24-4
Available Sizes
Curated Selection
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