Anti-Hu CD303 APC
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
CD303 ectodomain fused with human IgG Fc domain
Target Antigen
CD303
Clone
15E3
Applications
FC (QC tested)
Format
APC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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