Cefiderocol
Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
Product Specifications
CAS Number
1225208-94-5
Product Name Alternative
S-649266
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cefiderocol.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 1.06 mg/mL (ultrasonic)
Smiles
O=C(C(N12)=C(C[N+]3(CCNC(C4=CC=C(O)C(O)=C4Cl)=O)CCCC3)CS[C@]2([H])[C@H](NC(/C(C5=CSC(N)=N5)=N\OC(C)(C(O)=O)C)=O)C1=O)[O-]
Molecular Formula
C30H34ClN7O10S2
Molecular Weight
752.21
Precautions
H302, H312, H332
References & Citations
[1]Ito A, et al. In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria. Antimicrob Agents Chemother. 2017 Dec 21;62 (1) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Available Sizes
Frequently Asked Questions
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