Cefiderocol

Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.

Product Specifications

CAS Number

[1225208-94-5]

Product Name Alternative

S-649266

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefiderocol.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 1.06 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(C[N+]3(CCNC(C4=CC=C(O)C(O)=C4Cl)=O)CCCC3)CS[C@]2([H])[C@H](NC(/C(C5=CSC(N)=N5)=N\OC(C)(C(O)=O)C)=O)C1=O)[O-]

Molecular Formula

C30H34ClN7O10S2

Molecular Weight

752.21

Precautions

H302, H312, H332

References & Citations

[1]Ito A, et al. In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria. Antimicrob Agents Chemother. 2017 Dec 21;62 (1) .