BCL6-IN-6
BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6) . BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL) [1].
Product Specifications
CAS Number
2408882-54-0
UNSPSC
12352005
Target
BCL6
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl6-in-6.html
Purity
98.10
Solubility
DMSO : ≥ 4 mg/mL
Smiles
O=C(C1=CC=C(C2=CCCC2)S1)NC3=CC=C(NC4=NC(N5C[C@@H](C)N[C@@H](C)C5)=NC=C4F)C=C3OC
Molecular Formula
C27H31FN6O2S
Molecular Weight
522.64
References & Citations
[1]Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63 (2) :676-695.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
4101180 20 Channels
WSF-2000MH-20W Fermograph III - Fermentation System
Sign In for Pricing
View Details 
BNC881777-100 1x 100 µL
Prostate Specific Antigen (PSA) (3E6), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
