IDO-IN-5
IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.
Product Specifications
CAS Number
[1402837-79-9]
Product Name Alternative
NLG-1489
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO-IN-5.html
Purity
99.90
Solubility
10 mM in DMSO
Smiles
O[C@H](CC1)CC[C@]1([H])[C@H](O)C[C@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3
Molecular Formula
C18H21FN2O2
Molecular Weight
316.37
References & Citations
[1]Mario Mautino, et al. Fused imidazole derivatives useful as ido inhibitors. WO 2012142237 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO
Available Sizes
Curated Selection
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