ORC3L Rabbit Polyclonal Antibody
Rabbit polyclonal antibody to ORC3 also known as Origin recognition complex subunit Latheo, whose expression can be detected in the eye and duodenum but is highly expressive in the dura mater and dorsal thalamus. It is found in the nucleus. This protein is a component of the origin recognition complex (ORC) that binds origins of replication while DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Product Specifications
Product Name Alternative
Anti-LAT antibody, anti-LATHEO antibody, anti-ORC3 antibody, anti-ORC3L antibody
UniProt
Q9UBD5
Reactivity
Human
Target
ORC3
Clonality
Polyclonal
Conjugation
Unconjugated
Sequence
Synthetic peptide located within the following region: VVTAAEKMDANSATSEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVA
Field of Research
Cell Biology
Purification
Affinity Purified
Concentration
0.5 - 1 mg/ml
Form
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Molecular Weight
82kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Bovine, Canine, Equine, Guinea pig, Mouse, Porcine, Rabbit, Rat, Yeast, Zebrafish
Tested Applications
WB
NCBI Accession Number
NP_862820
Host or Source
Rabbit
Preservative
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Frequently Asked Questions
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