Fosmidomycin
Product Specifications
UNSPSC Description
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC50s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model[1].
Target Antigen
Antibiotic; Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fosmidomycin.html
Smiles
OP(O)(CCCN(C=O)O)=O
Molecular Weight
183.10
References & Citations
[1]Wiesner J, et al., In vitro and in vivo synergy of fosmidomycin, a novel antimalarial drug, with clindamycin. Antimicrob Agents Chemother. 2002 Sep;46(9):2889-94.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134914/Fosmidomycin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134914/
Clinical Information
Phase 3
CAS Number
66508-53-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
PAB940Hu01-01 20 µL
Polyclonal Antibody to Tissue Factor Pathway Inhibitor 2 (TFPI2)
Ask
View Details 
PAB940Hu01-02 100 µL
Polyclonal Antibody to Tissue Factor Pathway Inhibitor 2 (TFPI2)
Ask
View Details PAB940Hu01-03 200 µL
Polyclonal Antibody to Tissue Factor Pathway Inhibitor 2 (TFPI2)
Ask
View Details PAB940Hu01-04 1 mL
Polyclonal Antibody to Tissue Factor Pathway Inhibitor 2 (TFPI2)
Ask
View Details