(1R,2S,7R) -Sitafloxacin-d4 (hydrochloride)
(1R,2S,7R) -Sitafloxacin-d4 hydrochloride is deuterium labeled (1R,2S,7R) -Sitafloxacin hydrochloride (HY-B0395D) . (R) -Sitafloxacin (DU-6857), a stereoisomer of Sitafloxacin (DU-6859a), is also an inhibitor of topoisomerases, with an IC50 of 0.18 μg/mL of DNA gyrase[1].
Product Specifications
Product Name Alternative
(1R,2S,7R) -DU6859a-d4 (hydrochloride)
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@@H]4N)CC54C([2H])([2H])C5([2H])[2H])=C3Cl)C1=O)O.Cl
Molecular Formula
C19H15D4Cl2F2N3O3
Molecular Weight
450.30
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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