L-Pyroglutamic acid-13C5

L-Pyroglutamic acid-13C5 is the 13C labeled L-Pyroglutamic acid (HY-76082) [1]. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) [2].

Product Specifications

CAS Number

[55443-56-6]

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-pyroglutamic-acid-13c5.html

Purity

0.9966

Smiles

O[13C]([13C@H]1N[13C]([13CH2][13CH2]1)=O)=O

Molecular Formula

13C5H7NO3

Molecular Weight

134.08

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Zhang Q, et al., Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus. Rheumatology (Oxford) . 2021 Feb 1;60 (2) :598-606.|[3]Jiménez-Arias D, et al. Lettuce plants treated with L-pyroglutamic acid increase yield under water deficit stress[J]. Environmental and experimental botany, 2019, 158: 215-222.