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(E/Z) -Sulfosuccinimidyl oleate (sodium)

(E/Z) -Sulfosuccinimidyl oleate sodium is a racemic compound of (E) -Sulfosuccinimidyl oleate sodium and (Z) -Sulfosuccinimidyl oleate sodium isomers. Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Sulfosuccinimidyl oleate sodium has anti-inflammatory effect[1][2].

Product Specifications

CAS Number

1212012-37-7

Product Name Alternative

(E/Z) -Sulfo-N-succinimidyl oleate (sodium)

UNSPSC

12352005

Target

Mitophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/e-z-sulfosuccinimidyl-oleate-sodium.html

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CCCCCCCC/C=C/CCCCCCCC(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)=O

Molecular Formula

C22H36NNaO7S

Molecular Weight

481.58

References & Citations

[1]Dhungana H, et al. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017 Dec 4;14 (1) :237. |[2]Drahota Z, et al. Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain. Biochem Biophys Res Commun. 2010 Jan 15;391 (3) :1348-51.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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