α5β1 integrin agonist-1
Product Specifications
UNSPSC Description
α5β1 integrin agonist-1, acting as α5β1 integrin agonist, is able to selectively deliver 5-FU into tumor cells, successfully leading to cancer cell death.
Target Antigen
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/α5β1-integrin-agonist-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C[C@H]1N(C([C@]1([H])[C@@H](C)OC(CCNC(CN2C(NC(C(F)=C2)=O)=O)=O)=O)=O)C(NC3=C(C=CC=C3)C)=O)=O
Molecular Weight
547.49
References & Citations
[1]Baiula M, et al. Selective Integrin Ligands Promote Cell Internalization of the Antineoplastic Agent Fluorouracil. ACS Pharmacol Transl Sci. 2021 Sep 2;4(5):1528-1542.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139702/α5β1-integrin-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139702/α5β1-integrin-agonist-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2756557-83-0
Available Sizes
Curated Selection
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