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Mal-C5-Gly-Gly-Phe-MMAE

Mal-C5-Gly-Gly-Phe-MMAE (Compound S5) is a drug-linker conjugate for ADC. Mal-C5-Gly-Gly-Phe-MMAE consists of MMAE and a linker. Mal-C5-Gly-Gly-Phe-MMAE can be used for synthesis of ADCs and for cancer research[1].

Product Specifications

CAS Number

3056230-14-6

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-c5-gly-gly-phe-mmae.html

Smiles

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C([C@H](CC(C)C)NC([C@@H](NC(CNC(CNC(CCCCCN3C(C=CC3=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)OC)=O

Molecular Formula

C68H104N10O14

Molecular Weight

1285.61

References & Citations

[1]LIU Y, et al. LINKER AND DRUG CONJUGATE USING SAME, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF. WO2024188314. 2024 September 19.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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