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GRK1/2 (Phospho-Tyr13) rabbit pAb

Product Specifications

Background

G protein-coupled receptor kinase 2 (GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]

Product Name Alternative

Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)

Gene ID

156

Swiss Prot

P25098

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Dilution

WB 1:500-2000

Buffer

Liquid in PBS containing 50% glycerol, and 0.216% sodium azide.

Storage Conditions

-20°C/1 year

Available Sizes

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