Torin 2

[1]Liu Q, et al. Discovery of 9- (6-aminopyridin-3-yl) -1- (3- (trifluoromethyl) phenyl) benzo[h][1,6]naphthyridin-2 (1H) -one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer. J Med Chem. 2011 Mar 10;54 (5) :1473-80.|[2]Liu Q, et al. Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR. Cancer Res. 2013 Apr 15;73 (8) :2574-86.|[3]Codeluppi S, et al. Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling. PLoS One. 2014 Mar 25;9 (3) :e92649.|[4]Wang X, et al. mTORC signaling in hematopoiesis. Int J Hematol. 2016 May;103 (5) :510-8.