TRAF1 Polyclonal Antibody
Product Specifications
Background
TNF receptor associated factor 1 (TRAF1) Homo sapiens The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV) . EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have
Product Name Alternative
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene ID
7185
Swiss Prot
Q13077
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
46
Storage Conditions
-20°C/1 year
Protein Weight
46
Available Sizes
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