STIP1/HOP Rabbit pAb
Product Specifications
Background
Stress induced phosphoprotein 1 (STIP1) Homo sapiens STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]) .[supplied by OMIM, Jul 2009]
Product Name Alternative
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521) ; YM33122
Gene ID
10963
Swiss Prot
P31948
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; WB
Dilution
IHC-p1:50-200 , WB 1:1000-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.82% sodium azide.
Molecular Weight
64
Storage Conditions
-20°C/1 year
Protein Weight
64
Available Sizes
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