RUBIC rabbit pAb
Product Specifications
Background
The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Product Name Alternative
Run domain Beclin-1 interacting and cystein-rich containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron)
Gene ID
9711
Swiss Prot
Q92622
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.290% sodium azide.
Molecular Weight
105
Storage Conditions
-20°C/1 year
Protein Weight
105
Available Sizes
Frequently Asked Questions
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