R4RL2 Polyclonal Antibody

Function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system., PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein., similarity:Belongs to the Nogo receptor family., similarity:Contains 8 LRR (leucine-rich) repeats., subcellular location:Localized to the surface of neurons, including axons., tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.