PKN3 Polyclonal Antibody
Product Specifications
Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein., domain:The C1 domain does not bind the diacylglycerol (DAG) ., enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation., function:Contributes to invasiveness in malignant prostate cancer., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 protein kinase domain., similarity:Contains 3 REM (Hr1) repeats., subcellular location:Nuclear and perinuclear Golgi region., tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
Gene ID
29941
Swiss Prot
Q6P5Z2
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
97
Storage Conditions
-20°C/1 year
Protein Weight
97
Available Sizes
Curated Selection
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