PAR6G Polyclonal Antibody

Domain:The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases., function:Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins., similarity:Belongs to the PAR6 family., similarity:Contains 1 OPR domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 pseudo-CRIB domain., subunit:Interacts with PARD3 (Probable) . Interacts with GTP-bound forms of CDC42, ARHQ/TC10 and RAC1. Interacts with the N-terminal part of PRKCI and PRKCZ., tissue specificity:Widely expressed, with a higher expression in fetal and adult kidney.