NRX1B Polyclonal Antibody

Alternative products:A number of isoforms are produced by alternative promoter usage including the alpha-type (shown here) and beta-type (AC P58400) isoforms which differ in their N-terminus. Additional isoforms may be produced by alternative splicing, alternative products:A number of isoforms, alpha-type (AC Q9ULB1) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus, function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling., function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling., PTM:Highly O-glycosylated and minor N-glycosylated., PTM:N- and O-glycosylated., similarity:Belongs to the neurexin family., similarity:Contains 1 laminin G-like domain., similarity:Contains 3 EGF-like domains., similarity:Contains 6 laminin G-like domains., subunit:The cytoplasmic C-terminal region binds to CASK, CASKIN1 and APBA1. The laminin G-like domain 2 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan and to alpha-latroxin. Interacts with SYT13 and SYTL1., subunit:The cytoplasmic C-terminal region binds to CASK. Isoforms Beta 4b bind neuroligins NLGN1, NLGN2 and NLGN3, alpha-dystroglycan and alpha-latrotoxin., tissue specificity:Heart and brain.