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NR1H2 Polyclonal Antibody

Product Specifications

Background

Nuclear receptor subfamily 1 group H member 2 (NR1H2) Homo sapiens The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]) .[supplied by OMIM, Jan 2010]

Gene ID

7376

Swiss Prot

P55055

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Molecular Weight

50

Storage Conditions

-20°C/1 year

Protein Weight

50

Available Sizes

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