NFE2 Polyclonal Antibody
Product Specifications
Background
Function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity) . Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis.
Gene ID
4778
Swiss Prot
Q16621
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
41
Storage Conditions
-20°C/1 year
Protein Weight
41
Available Sizes
Curated Selection
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