INSRR Polyclonal Antibody

Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., function:This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 3 fibronectin type-III domains., subunit:Probable tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain.