HXB3 Polyclonal Antibody

Homeobox B3 (HOXB3) Homo sapiens This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) . [provided by RefSeq, Jul 2008]