CMTA1 Polyclonal Antibody

Disease:Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma., function:Transcriptional activator. May act as a tumor suppressor., induction:Detected at low levels at interphase and in resting cells. Up-regulated during S-phase and mitosis. Levels decrease at the end of mitosis., similarity:Belongs to the CAMTA family., similarity:Contains 1 CG-1 DNA-binding domain., similarity:Contains 1 IPT/TIG domain., similarity:Contains 3 ANK repeats., similarity:Contains 3 IQ domains., subunit:May interact with calmodulin ., tissue specificity:Detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen, heart and kidney. Detected in neuroblastic-type cultured neuroblastoma cells.