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CBX8 Polyclonal Antibody

Product Specifications

Background

Function:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility., similarity:Contains 1 chromo domain., subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1/hPRC-H) at least composed of PCGF2/RNF110, BMI1/PCGF4, CBX2/M33, CBX4/PC2, CBX8/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2/RING2. Interacts with MLLT3.

Gene ID

57332

Swiss Prot

Q9HC52

Cross Reactivity

Human; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Molecular Weight

42

Storage Conditions

-20°C/1 year

Protein Weight

42

Available Sizes

Curated Selection

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