ANR28 Polyclonal Antibody
Product Specifications
Background
Function:Putative regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation., similarity:Contains 27 ANK repeats., subcellular location:Seems to be excluded from nucleoli., subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS) . Interacts with PPP1C and HNRPK. Interacts with PPP6C, SAPS1 and SAPS3.
Gene ID
23243
Swiss Prot
O15084
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
115
Storage Conditions
-20°C/1 year
Protein Weight
115
Available Sizes
Curated Selection
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