PTP1B-IN-15
PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) . PTP1B-IN-15 has the potential for the research of type II diabetes and obesity[1].
Product Specifications
CAS Number
[765317-71-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/ptp1b-in-15.html
Purity
99.95
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CCC1=C(C(C2=CC(Br)=C(O)C(Br)=C2)=O)C(C=CC(S(=O)(N(C)C)=O)=C3)=C3O1
Molecular Formula
C19H17Br2NO5S
Molecular Weight
531.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Kamerlin SC, et al. A molecular dynamics study of WPD-loop flexibility in PTP1B. Biochem Biophys Res Commun. 2007;356 (4) :1011-1016.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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