PTP1B-IN-15

PTP1B-IN-15 is a potent and selective inhibitor of protein tyrosine phosphatase 1B (PTP1B) . PTP1B-IN-15 has the potential for the research of type II diabetes and obesity[1].

Product Specifications

CAS Number

[765317-71-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/ptp1b-in-15.html

Purity

99.95

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CCC1=C(C(C2=CC(Br)=C(O)C(Br)=C2)=O)C(C=CC(S(=O)(N(C)C)=O)=C3)=C3O1

Molecular Formula

C19H17Br2NO5S

Molecular Weight

531.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Kamerlin SC, et al. A molecular dynamics study of WPD-loop flexibility in PTP1B. Biochem Biophys Res Commun. 2007;356 (4) :1011-1016.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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