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MEK-5 Polyclonal Antibody

Product Specifications

Background

Mitogen-activated protein kinase kinase 5 (MAP2K5) Homo sapiens The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]

Product Name Alternative

MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5; YM3436

Gene ID

5067

Swiss Prot

Q13163

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF (paraffin section)

Dilution

WB: 1:1000-2000 IHC: 1:200-500

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Molecular Weight

49

Storage Conditions

-20°C/1 year

Protein Weight

49

Available Sizes

Curated Selection

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