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Kv1.8 Polyclonal Antibody

Product Specifications

Background

Potassium voltage-gated channel subfamily A member 10 (KCNA10) Homo sapiens Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA

Product Name Alternative

Potassium voltage-gated channel subfamily A member 10 (Voltage-gated potassium channel subunit Kv1.8) ; YM3575

Gene ID

3744

Swiss Prot

Q16322

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF (paraffin section)

Dilution

WB 1:1000-2000, IHC 1:100-200

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

58

Storage Conditions

-20°C/1 year

Protein Weight

58

Available Sizes

Curated Selection

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