TLE2 Polyclonal Antibody
Product Specifications
Background
Function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 6 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5., tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.
Product Name Alternative
TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2
Gene ID
7089
Swiss Prot
Q04725
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
110
Storage Conditions
-20°C/1 year
Protein Weight
110
Available Sizes
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