Tip5 Polyclonal Antibody

Function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3