Synuclein-α (phospho Tyr125) Polyclonal Antibody
Product Specifications
Background
Synuclein alpha (SNCA) Homo sapiens Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
Product Name Alternative
SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
Gene ID
6622
Swiss Prot
P37840
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
WB 1:500-2000 , Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR218574L4 10 µg
H2 (H2-Ke6) (NM_013543) Mouse Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
224581-01 50 µL
NONO (52kD Subunit, 54kD Nuclear RNA and DNA Binding Protein, 54kD Nuclear RNA- and DNA-Binding Protein, 55kD Nuclear Protein, DNA Binding p52/p100 Complex 52kD Subunit, DNA-Binding p52/p100 Complex, NMT 55, NMT55, Non Pou Domain Containing octamer (ATGCAAAT) Binding Protein, Non POU Domain Containing octamer Binding, Non POU Domain Containing octamer Binding Protein, Non-POU Domain-Containing octamer-Binding Protein, NONO, NonO Protein, NONO_HUMAN, NRB 54, NRB, NRB54, Nuclear RNA Binding Protein 54kD, P54, p54 (nrb), p54nrb, ) discontinued
Sign In for Pricing
View Details