STAT2 Polyclonal Antibody
Product Specifications
Background
Signal transducer and activator of transcription 2 (STAT2) Homo sapiens The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Product Name Alternative
STAT2; Signal transducer and activator of transcription 2; p113
Gene ID
6773
Swiss Prot
P52630
Cross Reactivity
Human
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
Western Blot: 1/500 - 1/2000
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
98
Storage Conditions
-20°C/1 year
Protein Weight
98
Available Sizes
Curated Selection
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