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SQSTM1/p62 (phospho-Ser349) rabbit pAb

Product Specifications

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]

Product Name Alternative

Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)

Gene ID

8878

Swiss Prot

Q13501

Cross Reactivity

Human; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Dilution

WB 1:1000-2000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

50

Storage Conditions

-20°C/1 year

Protein Weight

50

Available Sizes

Curated Selection

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