GSK932121
GSK932121 is an antimalarial drug with activity that inhibits the electron transport chain of P. falciparum. GSK932121 acts selectively on this pathogen at the level of cytochrome bc1 (complex III) . The synthesis method of GSK932121 is highly efficient, and the final structure can be obtained in only 5 steps. The synthesis of GSK932121 can be prepared atKilog scale to support clinical studies[1].
Product Specifications
CAS Number
958457-44-8
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gsk932121.html
Smiles
O=C1C(Cl)=C(C)NC(CO)=C1C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2
Molecular Formula
C20H15ClF3NO4
Molecular Weight
425.79
References & Citations
[1]Isoxazole mediated synthesis of 4- (1H) pyridones: improved preparation of antimalarial candidate GSK932121
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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