SLK Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Mediates apoptosis and actin stress fiber dissolution., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Proteolytically cleaved by caspase-3., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UVR domain., tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.