RANK Polyclonal Antibody
Product Specifications
Background
TNF receptor superfamily member 11a (TNFRSF11A) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Product Name Alternative
Tumor necrosis factor receptor superfamily member 11A (Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD antigen CD265)
Gene ID
8792
Swiss Prot
Q9Y6Q6
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
66
Storage Conditions
-20°C/1 year
Protein Weight
66
Available Sizes
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