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PPAR α (Phospho Ser21) rabbit pAb

Product Specifications

Background

Function:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids., online information:Peroxisome proliferator-activated receptor entry, similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain., subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13., tissue specificity:Skeletal muscle, liver, heart and kidney.

Product Name Alternative

Peroxisome proliferator-activated receptor alpha (PPAR-alpha; Nuclear receptor subfamily 1 group C member 1)

Gene ID

5465

Swiss Prot

Q07869

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

52

Storage Conditions

-20°C/1 year

Protein Weight

52

Available Sizes

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