PEPC Polyclonal Antibody
Product Specifications
Background
Progastricsin (PGC) Homo sapiens This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Product Name Alternative
PGC; Gastricsin; Pepsinogen C
Cross Reactivity
Plants
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB: 1:2000-5000
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
105-109
Storage Conditions
-20°C/1 year
Protein Weight
105-109
Available Sizes
Curated Selection
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