OAS2 Polyclonal Antibody
Product Specifications
Background
2'-5'-oligoadenylate synthetase 2 (OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Product Name Alternative
OAS2; 2'-5'-oligoadenylate synthase 2; (2-5') oligo (A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
Gene ID
4939
Swiss Prot
P29728
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
82
Storage Conditions
-20°C/1 year
Protein Weight
82
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
