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MLH1 Polyclonal Antibody

Product Specifications

Background

MutL homolog 1 (MLH1) Homo sapiens This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]

Product Name Alternative

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Gene ID

4292

Swiss Prot

P40692

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IF/ICC; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

85

Storage Conditions

-20°C/1 year

Protein Weight

85

Available Sizes

Curated Selection

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