JMY Polyclonal Antibody
Product Specifications
Background
Function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage., induction:By E2F., PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response., similarity:Contains 1 WH2 domain., subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.
Product Name Alternative
JMY; Junction-mediating and -regulatory protein
Gene ID
133746
Swiss Prot
Q8N9B5
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
130
Storage Conditions
-20°C/1 year
Protein Weight
130
Available Sizes
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