JAK3 Polyclonal Antibody

Product Specifications

Background

Janus kinase 3 (JAK3) Homo sapiens The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]

Product Name Alternative

JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK

Gene ID

3718

Swiss Prot

P52333

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF/ICC; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.