IRF-3 (phospho Ser386) Polyclonal Antibody
Product Specifications
Background
Interferon regulatory factor 3 (IRF3) Homo sapiens This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Product Name Alternative
IRF3; Interferon regulatory factor 3; IRF-3
Gene ID
3661
Swiss Prot
Q14653
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
48-55kd
Storage Conditions
-20°C/1 year
Protein Weight
48-55kd
Available Sizes
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