IL-17Rα Polyclonal Antibody
Product Specifications
Background
Interleukin 17 receptor A (IL17RA) Homo sapiens Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
Product Name Alternative
Interleukin-17 receptor A (IL-17 receptor A; IL-17RA; CDw217; CD antigen CD217)
Gene ID
23765
Swiss Prot
Q96F46
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; WB
Dilution
IHC-p 1:50-200, WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
90
Storage Conditions
-20°C/1 year
Protein Weight
90
Available Sizes
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